Kosuke Tanabe

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Oral tolerance is a key feature of intestinal immunity, generating systemic tolerance to ingested antigens (Ag). Dendritic cells (DC) have been revealed as important immune regulators, however, the precise role of DC in oral tolerance induction remains unclear. We investigated the characteristics of DC in spleen, mesenteric lymph node (MLN), and Peyer's(More)
disease have resulted in a greater number of deaths attributed to PE in recent years in Japan.2 Whereas the early diagnosis and treatment of VTE can result in relatively good outcome, PE is a fatal disease characterized by a high rate of mortality; indeed, sudden death may be the presenting symptom of VTE.3 Early diagnosis and early treatment, including(More)
BACKGROUND Anticoagulation is recommended as standard of care for venous thromboembolism (VTE) (pulmonary embolism [PE]/deep vein thrombosis [DVT]), for which unfractionated heparin (UFH) and warfarin are used in Japan. In the multi-regional AMPLIFY study, a fixed-dose regimen of apixaban alone was non-inferior to conventional therapy for treatment of(More)
Mental State Transition Network (MSTN) is a basic concept of approximating to human psychological and mental responses. A stimulus calculated by Emotion Generating Calculations (EGC) method can cause the transition of mood from an emotional state to others. In this paper, the agent can interact with human to realize smooth communication by an adaptive(More)
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