• Publications
  • Influence
Importance of measuring pharmacologically active metabolites of edoxaban: development and validation of an ultra-high-performance liquid chromatography coupled with a tandem mass spectrometry method
TLDR
A validated UHPLC–MS/MS method to quantify simultaneously edoxaban and its more relevant M4-metabolite in human plasma providing complementary information about the inhibitory effect of this active metabolite in chronometric or chromogenic assays is developed.
Bis-tetrahydroisoquinoline derivatives: structure analysis of the three stereoisomers of 1,1'-(propane-1,3-diyl)-bis-(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline).
Crystal structure of the three stereoisomers of 1,1'-(propane-1,3-diyl)-bis-(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline) hydrochloride after resolution by semi-preparative chiral HPLC
Determination of the Absolute Configuration of Aegelinol by Crystallization of Its Inclusion Complex with β-Cyclodextrin
The absolute configuration and structure of aegelinol, a pyranocoumarin isolated from Ferulago asparagifolia Boiss (Apiaceae), has been determined by crystallography. Crystal structure of the
Crystallographic, UV spectroscopic and computational studies of the inclusion complex of α-cyclodextrin with p-aminobenzoic acid
Crystal structure of the cyclomaltohexaose (α-cyclodextrin, α-CD) inclusion complex with p-aminobenzoic acid (pABA) has been determined by X-ray diffraction. The host:guest stoichiometry is 1:1. The
Structural characterization of cyclodextrins: from inclusion complexes to Metal-Organic Frameworks (MOFs)
Cyclodextrins (CD) are cyclic oligosaccharides composed of six to more than sixty glucose units. α-CD, β-CD and γ-CD are well known CD consisting of 6, 7 and 8 glycopyranose units, respectively, that