Kosaku Katsura

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Valproic acid (VPA) is widely used to treat epilepsy and manic-depressive illness. Although VPA has been reported to exert a variety of biochemical effects, the exact mechanisms underlying its therapeutic effects remain elusive. To gain further insights into the molecular mechanisms of VPA action, a genetic screen for fission yeast mutants that show(More)
in zebrafish results in male sterility and aneuploid as well as triploid progeny in females ...... 1561—1569 TANGE, YOSHIE, AND OSAMI NIWA, Novel mad2 alleles isolated in a Schizosaccharomyces pombe ␥-tubulin mutant are defective in metaphase arrest activity, but remain functional for chromosome stability in unperturbed mitosis .. A balance between two(More)
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