Kornelia Hohaus

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BACKGROUND A central cognitive function of sleep is to consolidate newly acquired memories for long-term storage. Here, we investigated whether the overnight consolidation of declarative memory in patients with chronic sleep disturbances is impaired, owing to less slow wave sleep (SWS) and an increased cortisol release. METHODS Polysomnographic(More)
PURPOSE Advanced cutaneous T-cell lymphoma (CTCL) is a hard-to-treat condition. Complete response is rare even with polychemotherapy. The use of liposomal formulation anti-cancer drugs can improve the efficacy and the risk-benefit ratio. Liposomal doxorubicin was shown to be effective as a second-line treatment in CTCL. There is no data available on another(More)
OBJECTIVE To report clinical experience with the rare neuroendocrine Merkel cell carcinoma of the skin. SUBJECTS AND SETTING Seventeen patients with Merkel cell carcinoma of the skin treated at the Departments of Dermatology and ENT, Krankenhaus Dresden-Friedrichstadt, Dresden, Germany, during the years 1984-2000 were evaluated. METHODS A retrospective(More)
We report a 30-year-old-patient with penile sclerosing lipogranuloma following injections of Vaseline. He was successfully treated by complete surgical removal of the subcutaneous material and excision of atrophic skin, followed by penoplasty. Temporary impairment of wound healing was overcome by application of topical carbon dioxide gas. A brief review on(More)
Treatment of human colorectal carcinoma cells HT29 with specific antisense oligodeoxynucleotides led to a decreased Gal beta1,4GlcNAc alpha2,6 sialyltransferase activity on the level of protein expression as well as on the mRNA level. Antisense treatment did not effect cell viability or cell growth. Oligodeoxynucleotides which were complementary to the(More)
Ein35-jährigerPatient stellte sichmit seit 3 Monaten bestehenden, rezidivierend auftretenden Schwellungen und Hämatomen beider Unterund Oberschenkel vor. Bei Verdacht auf eine Pannikulitis wurde bereits extern über 5 Tage mit 50mg Prednisolon ohne Besserung therapiert. Es bestanden keine Vorerkrankungen, keine Medikamenteneinnahme und es habe kein Trauma(More)
We report on a 65-year-old diabetic patient, who developed a deep fungal infection in the beard region after initial therapy with systemic antibiotics and topical corticosteroids. We were able to isolate Trichophyton mentagrophytes and treated him successfully with terbinafine 250 mg day(-1) orally in combination with topical ciclopirox and polyhexanide. In(More)
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