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- Emmanuel Paradis, Julien Claude, Korbinian Strimmer
- Bioinformatics
- 2004

UNLABELLED
Analysis of Phylogenetics and Evolution (APE) is a package written in the R language for use in molecular evolution and phylogenetics. APE provides both utility functions for reading andâ€¦ (More)

- Heiko A. Schmidt, Korbinian Strimmer, Martin Vingron, Arndt von Haeseler
- Bioinformatics
- 2002

SUMMARY
TREE-PUZZLE is a program package for quartet-based maximum-likelihood phylogenetic analysis (formerly PUZZLE, Strimmer and von Haeseler, Mol. Biol. Evol., 13, 964-969, 1996) that providesâ€¦ (More)

- Juliane SchÃ¤fer, Korbinian Strimmer
- Statistical applications in genetics andâ€¦
- 2005

Inferring large-scale covariance matrices from sparse genomic data is an ubiquitous problem in bioinformatics. Clearly, the widely used standard covariance and correlation estimators are ill-suitedâ€¦ (More)

- Juliane SchÃ¤fer, Korbinian Strimmer
- Bioinformatics
- 2005

MOTIVATION
Genetic networks are often described statistically using graphical models (e.g. Bayesian networks). However, inferring the network structure offers a serious challenge in microarrayâ€¦ (More)

- Marit Ackermann, Korbinian Strimmer
- BMC Bioinformatics
- 2008

Analysis of microarray and other high-throughput data on the basis of gene sets, rather than individual genes, is becoming more important in genomic studies. Correspondingly, a large number ofâ€¦ (More)

- Korbinian Strimmer, Arndt von Haeseler
- Proceedings of the National Academy of Sciencesâ€¦
- 1997

We introduce a graphical method, likelihood-mapping, to visualize the phylogenetic content of a set of aligned sequences. The method is based on an analysis of the maximum likelihoods for the threeâ€¦ (More)

- Sofia Wichert, Konstantinos Fokianos, Korbinian Strimmer
- Bioinformatics
- 2004

MOTIVATION
Microarray experiments are now routinely used to collect large-scale time series data, for example to monitor gene expression during the cell cycle. Statistical analysis of this data posesâ€¦ (More)

- Anne-Laure Boulesteix, Korbinian Strimmer
- Briefings in Bioinformatics
- 2007

Partial least squares (PLS) is an efficient statistical regression technique that is highly suited for the analysis of genomic and proteomic data. In this article, we review both the theoryâ€¦ (More)

- Rainer Opgen-Rhein, Korbinian Strimmer
- BMC Systems Biology
- 2007

The use of correlation networks is widespread in the analysis of gene expression and proteomics data, even though it is known that correlations not only confound direct and indirect associations butâ€¦ (More)

- Korbinian Strimmer
- Bioinformatics
- 2008

UNLABELLED
False discovery rate (FDR) methodologies are essential in the study of high-dimensional genomic and proteomic data. The R package 'fdrtool' facilitates such analyses by offering aâ€¦ (More)