Konstantina Karathanou

Learn More
microRNAs (miRNAs) are short non-coding RNA species, which act as potent gene expression regulators. Accurate identification of miRNA targets is crucial to understanding their function. Currently, hundreds of thousands of miRNA:gene interactions have been experimentally identified. However, this wealth of information is fragmented and hidden in thousands of(More)
∗These authors have equally contributed to this paper. According to the central dogma of Biology it was commonly accepted that most of the genetic information was transacted by proteins. Recent experimental techniques revealed that the majority of mammalian genomes and other complex organisms are in fact transcribed into non-coding RNAs. Typically,(More)
Therapeutic targeting of tumor cells with drug nanocarriers relies upon successful interaction with membranes and efficient cell internalization. A further consideration is that engineered nanomaterials should not damage healthy tissues upon contact. A critical factor in this process is the external coating of drug delivery nanodevices. Using in silico, in(More)
  • 1