A sparse population of a few hundred primarily hypothalamic neurons forms the hub of a complex neuroglial network that controls reproduction in mammals by secreting the 'master molecule'… (More)
The transition to puberty and adult fertility both require a minimum level of energy availability. The adipocyte-derived hormone leptin signals the long-term status of peripheral energy stores and… (More)
Genetically-encoded biosensors are powerful tools for understanding cellular signal transduction mechanisms. In aiming to investigate cGMP signaling in neurones using the EGFP-based fluorescent… (More)
The chemical signalling molecule nitric oxide (NO), which freely diffuses through aqueous and lipid environments, subserves an array of functions in the mammalian central nervous system, such as the… (More)
Neurons expressing nitric oxide (NO) synthase (nNOS) and thus capable of synthesizing NO play major roles in many aspects of brain function. While the heterogeneity of nNOS-expressing neurons has… (More)
Proceedings of the National Academy of Sciences…
2016
The large-scale automation of neuroscience has enabled the construction of genome-wide atlases, of which the Allen Brain Atlas (ABA), which allows the 3D visualization of the expression profile of… (More)
Yif1B is an intracellular membrane-bound protein belonging to the Yip family, shown previously to control serotonin 5-HT1A receptor targeting to dendrites. Because some Yip proteins are involved in… (More)
In the version of this article initially published, the Figure 1e,f legend read, “Circulating levels of LH (left panels) and FSH (right panels) in GnRH cells of control (blue) and Dicer mutants… (More)