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PURPOSE Constitutive activation of epidermal growth factor receptor (EGFR) as a result of gene amplification, mutation, or overexpression of its ligands has been associated with response to EGFR(More)
Immune checkpoints are emerging treatment targets, but mechanisms underlying checkpoint expression are poorly understood. Since alterations in DNA repair genes have been connected to the efficacy of(More)
5508 Background: Constitutive activation of EGFR as a result of gene amplification, mutation or overexpression of its ligands has been associated with response to EGFR targeting strategies. The role(More)