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- Kongming Wu, Anping Li, +10 authors Richard G. Pestell
- Molecular and cellular biology
- 2006
Obstacles to the expansion of cells with proliferative potential include the induction of cell death, telomere-based senescence, and the pRb and p53 tumor suppressors. Not infrequently, the molecular… (More)
- Maofu Fu, M. Kalyana Kumar Rao, +7 authors Richard G. Pestell
- The Journal of biological chemistry
- 2004
The androgen receptor (AR) regulates ligand-dependent gene transcription upon binding specific DNA sequences. The AR conveys both trans-activation and trans-repression functions, which together… (More)
- Chenguang Wang, Nagarajan Pattabiraman, +17 authors Richard G. Pestell
- Molecular and cellular biology
- 2003
The cyclin D1 gene is overexpressed in human breast cancers and is required for oncogene-induced tumorigenesis. Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a nuclear receptor… (More)
- Kongming Wu, Xuanmao Jiao, +11 authors Richard G. Pestell
- The Journal of biological chemistry
- 2011
The cell fate determination factor Dachshund was cloned as a dominant inhibitor of the hyperactive epidermal growth factor receptor ellipse. The expression of Dachshund is lost in human breast cancer… (More)
- Juan Luis Jurat-Fuentes, Lohitash Karumbaiah, +9 authors Michael J Adang
- PloS one
- 2011
Development of insect resistance is one of the main concerns with the use of transgenic crops expressing Cry toxins from the bacterium Bacillus thuringiensis. Identification of biomarkers would… (More)
- Zuoren Yu, Chenguang Wang, +9 authors Richard G. Pestell
- The Journal of cell biology
- 2008
Decreased expression of specific microRNAs (miRNAs) occurs in human tumors, which suggests a function for miRNAs in tumor suppression. Herein, levels of the miR-17-5p/miR-20a miRNA cluster were… (More)
- Peter Neumeister, Fiona J Pixley, +8 authors Richard G. Pestell
- Molecular biology of the cell
- 2003
The cyclin D1 gene encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the retinoblastoma protein, thereby promoting cell-cycle progression. Cyclin D1 is overexpressed… (More)
- Kongming Wu, Ying Yang, +9 authors Richard G. Pestell
- The Journal of biological chemistry
- 2003
The vertebrate homologues of Drosophila dachsund, DACH1 and DACH2, have been implicated as important regulatory genes in development. DACH1 plays a role in retinal and pituitary precursor cell… (More)
- Chris Albanese, Kongming Wu, +13 authors Richard G. Pestell
- Molecular biology of the cell
- 2003
The Wnt/beta-catenin/Tcf and IkappaB/NF-kappaB cascades are independent pathways involved in cell cycle control, cellular differentiation, and inflammation. Constitutive Wnt/beta-catenin signaling… (More)
- P K T Wan, Yongjun Zhang, Kongming Wu, Minsong Huang
- Journal of economic entomology
- 2005
Seasonal levels of Bacillus thuringiensis (Bt) insecticidal protein and its control efficacy against Helicoverpa armigera (Hübner) in Bt transgenic cotton GK19 (carrying a Cry1Ac/Cry1Ab fused gene)… (More)