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OBJECTIVE To study the effectiveness of Child Development Centre (CDC) model early stimulation therapy done in the first year of postnatal life, in improving the developmental outcome of at-risk neonates at one and two years of age. DESIGN Randomized controlled trial. SETTING AND SUBJECTS The study participants included a consecutive sample of 800(More)
OBJECTIVE To study the menstrual problems and menstrual hygiene practices of adolescent girls in Thiruvananthapuram City Corporation. METHODS Students of class XI and XII in the age group 15-19 years, belonging to ten Higher Secondary Schools within the Thiruvananthapuram City Corporation area were selected for the study by multistage sampling procedure(More)
Plasma and erythrocyte samples from acute post-streptococcal glomerulonephritis (APSGN) children and control children were enrolled in this study. Lipid peroxidation (LPO), measured in terms of thiobarbituric acid-reactive substances (TBARS) was found to be significantly increased in plasma and RBCs of APSGN children (P<0.05) than in control children.(More)
We describe our five year experience of conducting developmental evaluation clinic at CDC. We have also assessed the prevalence of developmental delay (defined as delay in any two areas in Denver Development Screening Test II [DDST II]), documented the possible prenatal, natal, postnatal risk factors for developmental delay and, also identified the pattern(More)
12-lipoxygenase (12-LOX) pathway which produces 12-HETE and hepoxiline HXA3 and HXB3, and induces production of reactive oxygen species and inflammation is increasingly being implicated in variety of cancers, including those of colorectal and thyroid cancers. Hence, we examined whether the functional polymorphism of 12-LOX (mRNA A835G; Protein Gln261Arg)(More)
Chronic Obstructive Pulmonary Disease (COPD), a progressive and partially reversible disease, has drawn world-wide attention for its moderate prevalence rate and causing central and peripheral neuropathy. Considering its severity in causing visual pathway impairment, the present investigation was carried out to find out the functional integrity of the(More)
Traditional teaching is that signet ring cells are the hall-mark of ovarian metastatic tumours. Paracentesis done for therapeutic purpose showed these cells and momentarily misled us. Other differentiating data are important in the correct management of cases with signet ring cells found in either ascitic fluid or on histopathologic examination.
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