Halophilic β-lactamase (BLA) has been successfully used as a novel fusion partner for soluble expression of aggregation-prone foreign proteins in Escherichia coli cytoplasm (Appl Microbiol Biotechnol 86:649–658, 2010b). This halophilic BLA fusion technology was applied here for secretory expression in Brevibacillus. The “Brevibacillus in vivo cloning”… (More)
Resistance to or relapse after androgen deprivation therapy (ADT) remains a significant problem in patients with prostate cancer. Several studies have hypothesized that the overexpression of MET and the activating signaling axis in prostate cancer cells are associated with castration-resistant prostate cancer (CRPC). On the other hand, the expression of… (More)
This paper describes our video summarization system using a model selection technique to estimate the optimal number of scenes for a summary. It uses a minimum description length as a model selection criterion and carries out two-stage estimation. First, we estimate the number of scenes in each shot, and then we estimate the number of scenes in a whole… (More)
A 33-year-old female presented with a rare synovial sarcoma manifesting as a painful 12 x 15 mm tumor in the median palmar carpus. Preoperative neurological examination detected only radiating spontaneous pain in her right radial palm and decreased right grasping power. Magnetic resonance (MR) imaging confirmed the presence of the tumor. The preoperative… (More)
To design and construct a novel bio-anode electrode based on the oxidation of glutamic acid to produce 2-oxoglutarate, generating two electrons from NADH. Efficient enzyme reaction and electron transfer were observed owing to immobilization of the two enzymes using a mixed self-assembled monolayer. The ratio of the immobilized enzymes was an important… (More)
Hepatocyte growth factor (HGF) is a well-known multifunctional growth factor, and evidence has accumulated indicating that the HGF/MET (HGF receptor) signaling axis is involved in the progression of cancer. Macrophage-stimulating protein (MSP) is also known as a growth factor which activates not only macrophages but also cancer cells and osteoclasts through… (More)
The Tokyo Institute of Technology team participated in the high-level feature extraction, surveillance event detection pilot and Rushes summarization tasks for TRECVID2008. In the high-level feature (HLF) extraction task, we employed a framework using a tree-structured codebook and a node selection technique last year. This year we focused on the position… (More)
this natural 3D display system, a holographic optical element (HOE) overcomes conflicts between convergence and accommodation. Users experience clear stereoscopic vision, without glasses, of a broad field of view. With its multiple-focus HOE, the system offers two pairs of viewing points in back-and-forth or horizontal locations.