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  • Tatsuhiro Shibata, Tsutomu Ohta, +6 authors Setsuo Hirohashi
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 2008 (First Publication: 9 September 2008)
  • The nuclear factor E2-related factor 2 (Nrf2) is a master transcriptional activator of genes encoding numerous cytoprotective enzymes that are induced in response to environmental and endogenouslyExpand
  • Toshimi Takano, Yuichiro Ohe, +12 authors Tomohide Tamura
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2005 (First Publication: 1 October 2005)
  • PURPOSE To evaluate epidermal growth factor receptor (EGFR) mutations and copy number as predictors of clinical outcome in patients with non-small-cell lung cancer (NSCLC) receiving gefitinib. Expand
  • Yu Fujita, Shigehiro Yagishita, +11 authors Takahiro Ochiya
  • Biology, Medicine
  • Molecular therapy : the journal of the American…
  • 2015 (First Publication: 19 January 2015)
  • Programmed cell death ligand-1 (PD-L1) has recently gained considerable attention for its role in tumor immune escape. Here, we identify a miR-197/CKS1B/STAT3-mediated PD-L1 network in chemoresistantExpand