Koji Kashihara

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Unlike assistive technology for verbal communication, the brain-machine or brain-computer interface (BMI/BCI) has not been established as a non-verbal communication tool for amyotrophic lateral sclerosis (ALS) patients. Face-to-face communication enables access to rich emotional information, but individuals suffering from neurological disorders, such as ALS(More)
Although acute myocardial ischemia or infarction may induce the Bezold-Jarisch (BJ) reflex through the activation of serotonin receptors on vagal afferent nerves, the mechanism by which the BJ reflex modulates the dynamic characteristics of arterial pressure (AP) regulation is unknown. The purpose of this study was to examine the effects of the BJ reflex(More)
The duration of the enhancement of choice reaction task efficiency by physical exercise at lactate threshold was studied. After healthy male students completed the exercise or nonexercise (control) period for 10 min., they performed a three-choice reaction task for 20 min. The mean heart rate during the choice reaction task after the exercise was higher(More)
A cascade model comprised of a derivative filter followed by a nonlinear sigmoidal component reproduces the input size dependence of transfer gain in the baroreflex neural arc from baroreceptor pressure input to efferent sympathetic nerve activity (SNA). We examined whether the same model could predict the operating point dependence of the baroreflex neural(More)
Functional laterality of cardiac sympathetic nerve stimulation in chronotropic and inotropic effects is well known. Whether left (LSNA) and right (RSNA) cardiac sympathetic nerve activities show laterality during dynamic baroreflex activation remains to be determined. In nine anesthetized, vagotomized, and aortic-denervated rabbits, we randomly perturbed(More)
Neuronal uptake is the most important mechanism by which norepinephrine (NE) is removed from the synaptic clefts at sympathetic nerve terminals. We examined the effects of neuronal NE uptake blockade on the dynamic sympathetic regulation of the arterial baroreflex because dynamic characteristics are important for understanding the system behavior in(More)
A novel framework of circulatory equilibrium was developed by extending Guyton's original concept. In this framework, venous return (CO(V)) for a given stressed volume (V) was characterized by a flat surface as a function of right atrial pressure (P(RA)) and left atrial pressure (P(LA)) as follows: CO(V) = V/W - G(S)P(RA) - G(P)P(LA), where W, G(S), and(More)
To assist the judgment of human operators, a computer-aided drug delivery system with adaptive predictive control is suggested. The assisting system can predict future responses of a patient to drug infusions, calculate optimal inputs, and present those values on a monitor. Regardless of sudden disturbance such as bleeding, human operators of the(More)
Mental imagery is an important theme in psychology. Although the mental rotation task is well known, the complicated functions in mental images with higher spatial perception remain unknown. The aim of this study was to evaluate the task performances during the mental imaging of two- or three-dimensional shapes (14 healthy male students, M age = 24.2 yr.,(More)
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