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  • Taishiro Kishimoto, Koichiro Watanabe, Naoki Shimada, Kazuya Makita, Gohei Yagi, Haruo Kashima
  • Psychology, Medicine
  • The Journal of clinical psychiatry
  • 2008 (First Published: 15 March 2008)
  • OBJECTIVE An inhibitory effect of hyperprolactinemia on the hypothalamo-pituitary-gonadal axis has been suggested as a mechanism of bone loss in schizophrenia, but this has not been confirmed. InContinue Reading
  • Hiroyoshi Takeuchi, Takefumi Suzuki, +6 authors Hiroyuki Uchida
  • Psychology, Medicine
  • Schizophrenia bulletin
  • 2013 (First Published: 1 September 2013)
  • Impact of dose reduction of atypical antipsychotics on cognitive function has not been investigated in stable patients with schizophrenia. In this open-label, 28-week, randomized controlled trial,Continue Reading
  • Chisa Tsutsumi, Hiroyuki Uchida, Takefumi Suzuki, Koichiro Watanabe, Shitij Kapur
  • Psychology, Medicine
  • Schizophrenia Research
  • 2011 (First Published: 1 August 2011)
  • OBJECTIVE Most patients with schizophrenia first start with a single antipsychotic, and yet most finally end up 'switching' or using 'polypharmacy'. The objective of this study was to examine theContinue Reading
  • Hiroshi Uchida, Hiroyoshi Takeuchi, Ariel Graff-Guerrero, Takefumi Suzuki, Koichiro Watanabe, David C. Mamo
  • Psychology, Medicine
  • Journal of clinical psychopharmacology
  • 2011 (First Published: 1 August 2011)
  • Positron emission tomography (PET) studies proposed a therapeutic window of D2 receptor occupancy (65%-80%) of antipsychotics for the treatment of schizophrenia in young adults. However, thisContinue Reading
  • Hiroyuki Uchida, Hiroyoshi Takeuchi, Ariel Graff-Guerrero, Takefumi Suzuki, Koichiro Watanabe, David C. Mamo
  • Psychology, Medicine
  • Journal of clinical psychopharmacology
  • 2011 (First Published: 1 June 2011)
  • Measuring dopamine D₂ receptor occupancy levels using positron emission tomography (PET) is still widely unavailable. The objective of this study was to evaluate the accuracy of predicting D2Continue Reading