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P This paper presents an e cient method for manipulating very large Shared inary-Deciston Diagrams (SBDD'S) which am too large to be stored within main memory. In contrast that the conventional depth-first aigorithm causes random access of memory,, the proposed method is intended to cause sequential access of memory. The main idea o our method is level-i(More)
A nonlinear multivariate analysis, artificial autoassociative neural network (AANN), was applied to bioprocess fault detection. In an optimal production process of a recombinant yeast with a temperature controllable expression system, faults in test cases with faulty temperature sensors and plasmid instability of recombinant cells could be detected by the(More)
Deterioration of the swallowing function in elderly persons and drug refusal among the behavioral abnormalities in Alzheimer's disease (AD) are commonly reported. Therefore, we developed an easy-to-swallow jelly formulation of Donepezil HCl which AD patients can take as a dessert. The development process, however, was full of trade-off problems. (1) Need(More)
We investigate the effects of music therapy concerts, which were held 60 times over a four year period, 1992 to 1996, in Geiyo Psychiatric Hospital, Kochi Prefecture and found that; 1) Musicians who performed at the concerts were not only from Kochi prefecture but also from other prefectures (10 times) and from four foreign countries (7 times). 2) Live(More)
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