Koichi Shimizu

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The metazoan mitochondrial (mt) genome is typically a circular, double-stranded DNA molecule between 14 and 18 kb in size. This molecule encodes 37 genes: 13 protein genes, 2 ribosomal RNA genes, and 22 tRNA genes (Wolstenholme 1992). The order of these genes varies among metazoans (Boore 1999). The mt genomes of 14 insects have been completely sequenced.(More)
In this paper we propose a new Delay-PUF architecture that is expected to solve the current problem of Delay-PUF that it is easy to predict the relation between delay information and generated information. Our architecture exploits glitches that behave non-linearly from delay variation between gates and the characteristic of pulse propagation of each gate.(More)
The point-spread function (PSF) for transcutaneous fluorescent imaging was obtained as an analytical solution in a closed form. It is applicable to cases in which the optical property of the image-blurring turbid medium is considered to be fairly homogeneous. We proposed a technique to improve a transcutaneous image by using depth-dependent PSF. Contrast of(More)
A design methodology of Random Switching Logic (RSL) using CMOS standard cell libraries is proposed to counter power analysis attacks against cryptographic hardware modules. The original RSL proposed in 2004 requires a unique RSL-gate for random data masking and glitch suppression to prevent secret information leakage through power traces. However, our new(More)
[Purpose] This study verified that the smoothness of reaching movements is able to quantitatively evaluate the effects of two- and three-dimensional images on movement in healthy people. In addition, clinical data of cerebrovascular accident patients were also analyzed by the same method. [Subjects] Ten healthy adult volunteers and two male patients with(More)
Intrahepatic cholangiocarcinoma (ICC) with lymph node (LN) metastasis is generally associated with a poor prognosis. However, we treated ICC with LN metastasis successfully by surgery and postoperative immunotherapy in a 59-year-old woman. The immunotherapy consisted of CD3-activated T cells and tumor lysate- or peptide-pulsed dendritic cells. Pathological(More)
The recurrence rate after surgery in patients with hepatocellular carcinoma (HCC) is very high, while prognosis is quite poor. However, there is no standard treatment to prevent recurrence of HCC after a curative operation. In this study, we investigated the clinical utilization of an autologous tumor lysate-pulsed dendritic cell vaccine plus ex vivo(More)
BACKGROUND A simple method for the measurement of LDL particle sizes is needed in clinical laboratories because a predominance of small, dense LDL (sd LDL) has been associated with coronary heart disease. We applied dynamic light scattering (DLS) to measure lipoprotein particle sizes, with special reference to sd LDL. METHODS Human serum lipoproteins(More)