Kohshiro Fujisawa

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The ultrastructural changes seen in muscle fibres of aged rats have been studied and described in relation to the degree of fibre atrophy and to the involvement of the different fibre types. The ultrastructural abnormalities were classified into four different categories: (1) diffuse dilatation of sarcoplasmic reticulum, (2) streaming of Z-bands, (3)(More)
BACKGROUND Some 200 patients, including those with Alzheimer's disease and other types of dementia, stay year-round in Yokohama - Houyuu Hospital. They undergo computed tomography (CT) neuroradiological examination at least once or twice a year. For this study, the accumulative data, including clinical and neuroradiological, were analyzed. METHODS(More)
Clinical phenotypes of hereditary diffuse leukoencephalopathy with spheroids (HDLS), a familial progressive neurodegenerative disorder affecting the white matter of the brain, are heterogenous and may include behavioral and personality changes, memory impairment, parkinsonism, seizure, and spasticity. Thus, HDLS is frequently unrecognized and misdiagnosed.(More)
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