Kohichi Tosaka

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Inhibitory actions of urogastrone (UG) on gastric acid secretion induced by tetragastrin (TG), histamine (Hist) and carbachol (Cach) were compared with cimetidine (Cime), atropine (Atr), prostaglandin E2 (PGE2) and epidermal growth factor (EGF) in acute conscious fistula rats. The inhibitory actions of UG were TG greater than Cach greater than or equal to(More)
Measles skin lesions were studied by light and electron microscopy. In the epidermis multinucleated giant cells were observed just beneath the hypertrophic horney layer at the maximum stage of rash; they were believed to result by an abnormal process of hyper- or parakeratosis. Neither typical inclusions nor viral nucleocapsids could be detected in any part(More)
Measles skin lesions were studied by light and electron microscopy. In the epidermis multinucleated giant cells were observed just beneath the hypertrophic horney layer at the maximum stage of rash; they were believed to result by an abnormal process of hyper- or parakeratosis. Neither typical inclusions nor viral nucleocapsids could be detected in any part(More)
The skin lesions of varicella were studied by electron microscopy. Singlemembrane particles were the only type of viral particles present in the nucleus. Two modes of viral envelopment were observed; budding from the inner nuclear membrane, and budding from vacuole membranes of the cytoplasm. Tubular, filamentous structures, probably an aberrant form of the(More)
Immunofluorescent study was attempted to determine whether or not virus antigen were present in the epidermis of measles eruptions. The electron microscopic observations of the same materials were also performed to detect viral localization in affected skins. The failure to detect any virus antigen in affected eipdermis throughout all eruptive stages seems(More)
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