Various kinds of stress are thought to precipitate psychiatric disorders, such as major depression. Whereas studies in rodents have suggested a critical role of medial prefrontal cortex (mPFC) in stress susceptibility, the mechanism of how stress susceptibility is determined through mPFC remains unknown. Here we show a critical role of prostaglandin E(2)… (More)
Car navigation systems provide the best route to a destination quickly and effectively. However, during daily driving, this information is not necessary since drivers already know the route to the destination very well. In addition, it is time-consuming for drivers to input the destination. Thus, our research group has proposed a new car navigation system… (More)
Audio usage is one of the more widely-applicable methods of information presentation in wearable computing environments since it can be used hands-free, requires only small devices like earphones, and does not interfere with most tasks compared with other methods including visual displays. However, since presented sound is often drowned out by ambient noise… (More)
Because of advances in information technologies, car navigation systems have come into widespread use as useful tools to guide drivers where they want to go. Conventional car navigation systems present the most suitable route according to a destination input into the system. However, since the required operation to input the destination costs so much, users… (More)
Knowledge about the types of nests built by dinosaurs can provide insight into the evolution of nesting and reproductive behaviors among archosaurs. However, the low preservation potential of their nesting materials and nesting structures means that most information can only be gleaned indirectly through comparison with extant archosaurs. Two general nest… (More)
We define a new model structure on the category of small categories, which is intimately related to the notion of coverings and fundamental groups of small categories. Fibrant objects in the model structure coincide with groupoids, and the fibrant replacement is the groupoidification.
Tactile displays provoke tactile sensations by artificially stimulating tactile receptors. While many types of tactile displays have been developed, electrotactile displays that exploit electric stimulation can be designed to be thin, light, flexible and thus, wearable. However, the high voltages required to stimulate tactile receptors and limited varieties… (More)
Cyclooxygenase (COX)-2 selective inhibitors suppress non-alcoholic fatty liver disease (NAFLD); however, the precise mechanism of action remains unknown. The aim of this study was to examine how the COX-2 selective inhibitor nimesulide suppresses NAFLD in a murine model of high-fat diet (HFD)‑induced obesity. Mice were fed either a normal chow diet (NC), an… (More)