Kohei Nojima

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Pemphigus vulgaris is a serious autoimmune skin disorder associated with desmoglein 1 and 3. Selective plasma exchange (SePE) for pemphigus vulgaris remains unknown. We investigated the removal characteristics of pemphigus autoantibodies, immunoglobulins, and fibrinogen in three cases. When the mean processed volume for SePE was 1.2 plasma volumes, the mean(More)
Primary penile melanomas are rare tumors that represent less than 0.1% of all melanomas. We report a case of a 60-year-old Japanese male with a mucosal penile melanoma and describe an increased CD8(+) T cell infiltration in brain after dacarbazine (DTIC) administration. After partial penectomy and left inguinal lymphadenectomy, he developed multiple lung,(More)
Figure 1. (a) A 7 mm 9 5 mm pigmentary lesion on the patient’s right thumb. (b) Dermoscopy of the pigmentary lesion on the fingertip showing a parallel ridge pattern. (c) Histopathology showing pigmentation at the basal layer of the epidermis and vascular proliferations in the dermis (hematoxylin–eosin [HE], original magnification 940). (d) Vascular(More)
Dear Editor, A 50-year-old Japanese man consulted the local dermatology clinic for multiple painful skin ulcers on both legs in June 2015. He had been receiving hemodialysis for chronic renal failure due to diabetic nephropathy for 5 years. The patient also had hypertension, atrial fibrillation and dyslipidemia. Although oral antibiotics were administrated(More)