Kohei Miyata

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We have been investigating the potential use of cell-penetrating peptide-linked polymers as a novel penetration enhancer. Since previous in vivo studies demonstrated that poly(N-vinylacetamide-co-acrylic acid) bearing D-octaarginine, a typical cell-penetrating peptide, enhanced membrane permeation of biomolecules, its potential as an in vitro transfection(More)
In order to resolve the problem of recognizing blood cancer cells accurately and effectively, an identifying and classifying algorithm was proposed using grey level and color space. After image processing, blood cells images were gained by using denoising, smoothness, image erosion and so on. After that, we use granularity analysis method and morphology to(More)
The Thomsen-Friedenreich (TF) antigen represents a prognostic biomarker of colorectal carcinoma. Here, using a nanobeacon, the surface of which was fabricated with peanut agglutinin as TF-binding molecules, we demonstrate that the nanobeacon is able to detect TF antigen in frozen and freshly biopsied polyps using fluorescence microscopy. Our results provide(More)
Although industrial robots have developed considerably since the end of the last century, and have been used in various fields, robotics is still being actively researched in Japan. Following the work of national research institutes and educational institutions, robot manufacturers have also put considerable resources into developing a new generation of(More)
We evaluated cross-reactivity of immunoglobulin A (IgA) secreted on the nasal mucosa in mice that were nasally inoculated 4 times with a mixture of inactivated H1N1 influenza A viruses and poly(N-vinylacetamide-co-acrylic acid) (PNVA-co-AA) bearing d-octaarginine at 7-day intervals. Three viral strains (A/Puerto Rico/8/34, A/New Caledonia/20/99 IVR116, and(More)
Recently, new touch panels are actively developed. And, the device with the touch panel is widespread. However, past touch panels cannot fold. Therefore, they can be set up only on the plane. Flexibility is needed for the touch panel to set up the touch panel in various places. Then, we propose the flexible touch panel sensor. This sensor is made from a(More)
Mucosal vaccination is one of the most effective ways to reduce the risk of pandemics as a result of incorrect prediction of epidemic strains of influenza viruses or virus mutation. However, adjuvants and antigen carriers with potent immunostimulatory activities are a prerequisite for significant induction of mucosal immunity because most antigens are(More)
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