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  • Toshihiko Matsuura, Hiromichi Sakai, +4 authors Shigemi Norioka
  • Biology, Medicine
  • The Journal of biological chemistry
  • 2001 (First Published: 30 November 2001)
  • The crystal structure of the Pyrus pyrifolia pistil ribonuclease (S(3)-RNase) responsible for gametophytic self-incompatibility was determined at 1.5-A resolution. It consists of eight helices andContinue Reading
  • Go Ueno, Hiroyuki Kanda, Raita Hirose, Koh Ida, Takashi Kumasaka, Masaki Yamamoto
  • Biology, Medicine
  • Journal of Structural and Functional Genomics
  • 2005 (First Published: 1 March 2006)
  • RIKEN Structural Genomics Beamlines, BL26B1 & BL26B2 at the SPring-8, have been constructed for the structural genomics research. The main feature of the beamline is full automation of the successiveContinue Reading
  • Tomotaka Moriguchi, Koh Ida, Takaaki Hikima, Go Ueno, Masaki Yamamoto, Haruo Suzuki
  • Chemistry, Medicine
  • Journal of biochemistry
  • 2010 (First Published: 1 October 2010)
  • We characterized the crystal structures of heterotetrameric sarcosine oxidase (SO) from Corynebacterium sp. U-96 complexed with methylthioacetate (MTA), pyrrole 2-carboxylate (PCA) and sulphite, andContinue Reading
  • Tomoya Sameshima, Takeshi Yamamoto, +8 authors Ikuo Miyahisa
  • Chemistry, Medicine
  • Biochemistry
  • 2018 (First Published: 2 January 2018)
  • B-cell lymphoma 6 (BCL6) is the most frequently involved oncogene in diffuse large B-cell lymphomas (DLBCLs). BCL6 shows potent transcriptional repressor activity through interactions with itsContinue Reading
  • Koh Ida, Masaya Suguro, Haruo Suzuki
  • Chemistry, Medicine
  • Journal of biochemistry
  • 2011 (First Published: 31 August 2011)
  • The mature form of L-Phe oxidase of Pseudomonas sp. P-501 (PAOpt) catalyzes the oxygenative decarboxylation of L-Phe and the oxidative deamination of L-Met, and is highly specific for L-Phe. TheContinue Reading
  • Peng Li, Hailin Zheng, +14 authors Lawrence P. Wennogle
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 2016 (First Published: 11 February 2016)
  • A diverse set of 3-aminopyrazolo[3,4-d]pyrimidinones was designed and synthesized. The structure-activity relationships of these polycyclic compounds as phosphodiesterase 1 (PDE1) inhibitors wereContinue Reading