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BACKGROUND Hallucinations and delusions are frequent in patients with Parkinson disease (PD) and may have severe clinical consequences for those patients and their caregivers. However, the prevalence and clinical features of these symptoms have not been studied in a representative sample. OBJECTIVE To study the prevalence and clinical correlates of(More)
OBJECTIVE To characterize the psychosocial burden on spouses living with the elderly suffering from mild dementia, stroke and Parkinson's disease, and to identify patient characteristics associated with it. Materials and methods Data on patient-spouse couples came from three studies of patients with stroke (36 couples), mild dementia (92 couples) and(More)
OBJECTIVE To study the safety and efficacy of the cholinesterase inhibitor donepezil in patients with Parkinson's disease (PD) and cognitive impairment. METHODS This was a double blind, randomised and placebo controlled, crossover study in which 14 patients with PD and cognitive impairment received donepezil (5 or 10 mg per day) or matching placebo during(More)
The prevalence of dementia in the age group 75 and over was studied in a random sample of elderly living at home. The MMS and the GMS were used as screening instruments, supplemented by medical history and a physical examination. The dementia diagnosis was confirmed by psychogeriatric assessment and a follow-up after 18 months. The prevalence of dementia in(More)
BACKGROUND Evidence supports a role for the NMDA receptors in learning and memory. These can be modulated by the antibiotic D-cycloserine in such a way that the effect of the excitatory transmitter substance glutamate is enhanced. A study on healthy subjects pretreated with scopolamine to mimic Alzheimer's disease showed a positive effect of D-cycloserine(More)
OBJECTIVES To study how well the scoring on each item of the MMSE relates to the sum-score when the purpose is to identify persons with cognitive impairment, and to identify an equally effective subset of MMSE items for predicting cognitive impairment. DESIGN Retrospective survey of MMSE data for 850 elderly. SETTING A variety of clinical settings. (More)
OBJECTIVES To study whether a low, "normal" sumscore (i.e., 24 or higher) on the Mini-Mental Status Examination (MMSE) near the cutpoint usually employed for identifying persons with cognitive impairment predicts later development of dementia. DESIGN A prospective study of a random sample of nondemented persons aged 75 years and older, according to(More)
PURPOSE To explore how motor and cognitive impairments relate to physical activities of daily living (PADL) and social activities after stroke. METHOD The data related to 65 patients (mean age 74.4 years, 43% females), assessed 1 year after stroke by means of the Sødring Motor Evaluation of Stroke patients and the Assessment of Stroke and other Brain(More)
The validity and reliability of the Barthel index were studied in 60 geriatric patients, 87 stroke patients, and 102 patients with hip fracture, using a factor analysis methodology which explicitly accounts for the ordinal nature of the scoring on each item. The findings substantiate that the Barthel index is unidimensional among stroke patients, but not(More)
BACKGROUND AND PURPOSE Falls and their after-effects are important contributors to disability in old age, but may be mitigated. The relationship between self-reported health and functioning and falling is examined in the present study. METHOD The study design was cross-sectional. Data were collected from interviews with 431 community-dwelling Norwegian(More)