Knut Großmann

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Percutaneous transluminal angioplasty was used to treat atherosclerotic lesions in 22 brachiocephalic arteries in 20 patients during a 2 1/2 year period. Seven subclavian, 13 vertebral, one external carotid, and one common carotid arteries were involved. Nineteen arteries were successfully dilated, but dilatation of two vertebral arteries and attempted(More)
We present our experience with 105 patients in whom percutaneous transluminal angioplasty was performed in 112 stenosed or occluded supra-aortic arteries. Symptoms of cerebrovascular and/or vertebrobasilar insufficiency were present in 104 of the 105 patients. The angioplasty was successful in 35 stenoses of the internal carotid artery, 2 stenoses of the(More)
The human myocardium retains oPPA as opposed to pPPA. Therefore turnover of oPPA was compared with that of pPPA in rat hearts and in man, the latter by using substrates double-labeled with 123/131I and 14C. Moreover, substrate binding to coenzyme-A was tested in vitro. In rats, oPPA remained mainly in the pool of free fatty acids, as opposed to pPPA, which(More)
BACKGROUND Induced moderate hypothermia (HT) for 72 h has been shown to reduce the combined outcome of death or severe neurodevelopmental disabilities in asphyxiated full-term infants. A pathological amplitude integrated EEG background as early as 3-6 h after birth, has been shown to correlate to poor prognosis. AIM The aim of this study was to(More)
Service-oriented architectures (SOA) offer a conceptual and technical solution for many problems. However, the realization and even more the management of a SOA often remains a very hard task. A continuous evaluation of existing services and service candidates is necessary to implement, maintain and enhance a SOA. This is far from being trivial because of(More)
The aim of this study was to investigate, if the the combined treatment of compression stockings and drug treatment with oxerutins (O-(beta-hydroxyethyl)-rutosides, Venoruton) provides additional benefit for patients with chronic venous insufficiency (CVI) compared to compression treatment alone. Oxerutins belong to the group of oedema protective agents and(More)
Radioiodine labelled 17-iodo-heptadecanoic acid (IHA) is used for non-invasive study of myocardial metabolism in coronary heart disease and cardiomyopathy. Yet in the interpretation of in vivo myocardial tracer kinetics, it is controversial whether the intracellular degradation of IHA or the removal of iodide across cellular membranes is the rate-limiting(More)
Information models are seen as an important tool within the information systems discipline as well as in non-IS domains. However, modeling is a highly manual task and causes extensive effort. Modeling methods focus only on the creation of models, without giving concrete instructions of an appropriate use of them. An increased efficiency could be achieved if(More)