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ICA-based artefact removal and accelerated fMRI acquisition for improved resting state network imaging
The identification of resting state networks (RSNs) and the quantification of their functional connectivity in resting-state fMRI (rfMRI) are seriously hindered by the presence of artefacts, many ofExpand
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Magnetic resonance imaging studies in unipolar depression: Systematic review and meta-regression analyses
Previous meta-analyses of structural MRI studies have shown diffuse cortical and sub-cortical abnormalities in unipolar depression. However, the presence of duplicate publications, recruitment ofExpand
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Magnetic resonance imaging studies in bipolar disorder and schizophrenia: meta-analysis.
BACKGROUND Several magnetic resonance imaging (MRI) studies have identified structural abnormalities in association with bipolar disorder. The literature is, however, heterogeneous and there isExpand
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  • Open Access
CRP, IL-6 and depression: a systematic review and meta-analysis of longitudinal studies.
BACKGROUND Inflammatory markers are raised in cross-sectional studies of depressed patients and may represent an important mediating factor for behaviour, neural plasticity and brain structure. Expand
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A meta-analysis of diffusion tensor imaging in mild cognitive impairment and Alzheimer's disease
We reviewed case-control studies of diffusion tensor imaging (DTI) in patients with Alzheimer's dementia (AD) and mild cognitive impairment (MCI), in order to establish the relative severity andExpand
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Timing of onset of cognitive decline: results from Whitehall II prospective cohort study
Objectives To estimate 10 year decline in cognitive function from longitudinal data in a middle aged cohort and to examine whether age cohorts can be compared with cross sectional data to infer theExpand
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  • Open Access
White matter hyperintensities in late life depression: a systematic review
Background: White matter hyperintensities in MRI scans are age related but appear to be more prevalent in depressed patients. They may be more pronounced in late onset depression. This finding, ifExpand
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Blunted response to feedback information in depressive illness.
Depressive illness is associated with sustained widespread cognitive deficits, in addition to repeated experience of distressing emotions. An accepted theory, which broadly accounts for features ofExpand
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  • Open Access
Reduced in vivo binding to the serotonin transporter in the cerebral cortex of MDMA ('ecstasy') users.
BACKGROUND The use of MDMA ('ecstasy') is common among young people in Western countries. Animal models of MDMA toxicity suggest a loss of serotonergic neurons, and potentially implicate in theExpand
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Cumulative meta-analysis of interleukins 6 and 1β, tumour necrosis factor α and C-reactive protein in patients with major depressive disorder
Highlights • This meta-analysis confirms a robust link between IL-6, CRP and major depression.• The role of TNF-α and IL-1β in major depression remains uncertain.• Further mechanistic andExpand
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  • Open Access