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OBJECTIVES To evaluate glycosaminoglycan-dependent chemical exchange saturation transfer (gagCEST) imaging at 3-T magnetic resonance imaging (MRI) for quantification of glycosaminoglycan (GAG) content in intervertebral discs (IVDs) in patients with low-back pain (LBP). METHODS Sixteen patients with LBP were examined in this Institutional Review(More)
STUDY DESIGN A prospective clinical randomized controlled trial. OBJECTIVES To determine the long-term effect of a combined exercise and motivational program on the level of disability of patients with chronic and recurrent low back pain (LBP). SUMMARY OF BACKGROUND DATA There is agreement on the importance of exercise during the course of chronic LBP.(More)
BACKGROUND The purpose of our investigation was to compare quantitative T2 relaxation time measurement evaluation of lumbar intervertebral discs with morphological grading in young to middle-aged patients with low back pain, using a standardized region-of-interest evaluation approach. PATIENTS AND METHODS Three hundred thirty lumbar discs from 66 patients(More)
OBJECTIVE To correlate long-term clinical outcome and the results of morphological as well as advanced biochemical magnetic resonance imaging (MRI) techniques [T2-mapping, glycosaminoglycan chemical exchange saturation transfer (gagCEST), sodium-23-imaging] in patients after autologous osteochondral transplantation (AOT) in knee joints. METHOD Nine AOT(More)
PURPOSE To compare sodium imaging of lumbar intervertebral disks in asymptomatic volunteers at 7-T magnetic resonance (MR) imaging with quantitative T2 mapping and morphologic scoring at 3 T. MATERIALS AND METHODS Following ethical board approval and informed consent, the L2-3 to L5-S1 disks were examined in 10 asymptomatic volunteers (nine men, one(More)
PURPOSE The purpose was to investigate the in vivo effects of unloading and compression on T1-Gd relaxation times in healthy articular knee cartilage. MATERIALS AND METHODS Ten volunteers were enrolled, and dGEMRIC images of their right knee joints were obtained using 3.0-T MR at three timepoints: directly following exercise ("baseline"), approximately 15(More)
PURPOSE To demonstrate the value of multi detector computed tomography (MDCT) and magnetic resonance imaging (MRI) in the preoperative work up of temporal bone tumors and to present, especially, CT and MR image fusion for surgical planning and performance in computer assisted navigated neurosurgery of temporal bone tumors. MATERIALS AND METHODS Fifteen(More)
STUDY DESIGN Prospective in vivo study of meniscoids in the cervical zygapophyseal joints. OBJECTIVE To generate reference data for in vivo magnetic resonance (MR) imaging properties of meniscoids in the cervical zygapophyseal joints. SUMMARY OF BACKGROUND DATA Meniscoids, also called synovial folds, are tiny anatomic structures within the zygapophyseal(More)
BACKGROUND CONTEXT Diurnal changes in T2 values, indicative for changes in water content, have been reported in the lumbar intervertebral discs. However, data concerning short-term T2 changes are missing. PURPOSE The purpose of this study was to investigate the short-term effects of unloading on T2 values in lumbar intervertebral discs in vivo. STUDY(More)
Ultra-high-field magnetic resonance (MR) imaging provides a high signal-to-noise ratio and thus is expected to be superior to 1.5T and 3T MR systems that are currently used in daily routine. For use in the musculoskeletal system, expectations are high, particularly for smaller joints such as the wrist, because of the small size of the visualized anatomical(More)