Klaus Feldmann

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The presently short innovation cycles are one of the biggest challenges for companies. Therefore, not only time to market but also time for developing new products has to be shortened. To face this challenge, more and more software tools are used during the whole product synthesis. One of these tools is a product data management system for integration and(More)
The optimal dispatching of orders to the production system and the assignment of workpieces to machines is influenced by numerous disturbances at run time, which can neither be foreseen nor regarded in every detail with conventional strategies for coordination. Often, workflows are defined manually and therefore they implicate problems in adapting to(More)
In this paper, MIDCAD, an integrated design system for Molded Interconnect Devices, is presented and some important techniques for the development of this design system are discussed. A series of MID-related special functions and an integrated MID product model, which are not supported by conventional MCAD und ECAD systems, were developed in MIDCAD. Based(More)
The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor ZD1839 (Iressa®) reduces survival and augments radiation response of certain tumor cells. The aim of this study was to identify cellular events that are associated with the modulation of radiosensitivity by ZD1839. Three tumor cell lines (A549, H596, FaDu) were exposed to ionizing(More)