Learn More
In the German state of Rhineland-Palatinate, herds were identified that were likely to have a Neospora caninum sero-prevalence > or = 10% by using a bulk milk ELISA. Individual herd data were obtained by a questionnaire. Univariate logistic regression showed that bulk milk positive farms had a significantly higher chance to report an increased abortion rate(More)
In directed model checking, the traversal of the state space is guided by an estimate of the distance from the current state to the nearest error state. This paper presents a distance-preserving abstraction for concurrent systems that allows one to compute an interesting estimate of the error distance without hitting the state explosion problem. Our(More)
Stochastic branching processes are a classical model for describing random trees, which have applications in numerous fields including biology, physics, and natural language processing. In particular, they have recently been proposed to describe parallel programs with stochas-tic process creation. In this paper, we consider the problem of model checking(More)
In the present study, 132 selected faecal samples from clinically affected and subclinically infected cattle from dairy herds known to be affected by Johne's disease were investigated for the presence of Mycobacterium paratuberculosis using Ziehl-Neelsen staining, faecal culture and a commercially available DNA-Probe test. The sensitivity was 36.4% for(More)
Mycobacterium avium subsp. paratuberculosis (MAP) is the causal agent of Johne's disease in dairy cattle. Genotyping of MAP is useful to gain a better understanding of the origin of infection, to evaluate regional control programs, to improve diagnostics, and to develop vaccines. In this study 91 MAP isolates mainly from symptomatic dairy cattle in(More)
After immunization of four calves with a live modified Mycobacterium paratuberculosis vaccine the course of the humoral and cell mediated immune reactions was studied during a 2-year clinical investigation. Furthermore, the possibility of shedding of the vaccine strain and the influence of the vaccination on the tuberculin skin test was determined. In(More)
Systems and protocols combining concurrency and infinite state space occur quite often in practice, but are very difficult to verify automatically. At the same time, if the system is correct, it is desirable for a verifier to obtain not a simple " yes " answer, but some independently checkable certificate of correctness. We present SLAB — the first(More)
To obtain a rapid overview over the distribution of bovine Neospora caninum-infections in the German state of Rhineland-Palatinate, an ELISA to determine specific bovine antibodies against a p38 surface antigen of N. caninum tachyzoites was modified to examine bulk milk samples from cattle herds. Experimental bulk milk samples were used to demonstrate that(More)
UPPAAL/DMC is an extension of UPPAAL which provides generic heuristics for directed model checking. In this approach, the traversal of the state space is guided by a heuristic function which estimates the distance of a search state to the nearest error state. Our tool combines two recent approaches to design such estimation functions. Both are based on(More)