Klas H. Pettersen

Publications50
h-index18
Citations2,168
Highly Influential Citations171
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Current-source density estimation based on inversion of electrostatic forward solution: Effects of finite extent of neuronal activity and conductivity discontinuities
A new method for estimation of current-source density (CSD) from local field potentials is presented. This inverse CSD (iCSD) method is based on explicit inversion of the electrostatic forward… Expand
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Modeling the Spatial Reach of the LFP
The local field potential (LFP) reflects activity of many neurons in the vicinity of the recording electrode and is therefore useful for studying local network dynamics. Much of the nature of the LFP… Expand
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Intrinsic dendritic filtering gives low-pass power spectra of local field potentials
TLDR
The local field potential (LFP) is among the most important experimental measures when probing neural population activity, but a proper understanding of the link between the underlying neural activity and the LFP signal is still missing. Expand
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Amplitude variability and extracellular low-pass filtering of neuronal spikes.
The influence of neural morphology and passive electrical parameters on the width and amplitude of extracellular spikes is investigated by combined analytical and numerical investigations of… Expand
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LFPy: a tool for biophysical simulation of extracellular potentials generated by detailed model neurons
TLDR
We introduce LFPy, an open source Python package for numerical simulations of extracellular potentials stemming from neural activity in brain tissue. Expand
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Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow
Significance Transport of nutrients and clearance of waste products are prerequisites for healthy brain function. It is still debated whether solutes are transported through the interstitial space by… Expand
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Laminar population analysis: estimating firing rates and evoked synaptic activity from multielectrode recordings in rat barrel cortex.
We present a new method, laminar population analysis (LPA), for analysis of laminar-electrode (linear multielectrode) data, where physiological constraints are explicitly incorporated in the… Expand
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Frequency Dependence of Signal Power and Spatial Reach of the Local Field Potential
Despite its century-old use, the interpretation of local field potentials (LFPs), the low-frequency part of electrical signals recorded in the brain, is still debated. In cortex the LFP appears to… Expand
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Estimation of population firing rates and current source densities from laminar electrode recordings
TLDR
This model study investigates the validity of methods used to interpret linear (laminar) multielectrode recordings. Expand
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Handbook of Neural Activity Measurement: Extracellular spikes and CSD
TLDR
Extracellular recordings with multi-shank electrodes can be used to sort out spike trains from tens of neurons from single tetrodes and from hundreds of neurons with multi shank electrodes. Expand
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