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G protein-coupled receptors (GPCRs) oligomerization has emerged as a vital characteristic of receptor structure. Substantial experimental evidence supports the existence of GPCR-GPCR interactions in… Continue Reading
RationaleProlonged social isolation has been reported to induce different behavioral disturbances, among the most consistent of which are the increased locomotor response to novelty and the effects… Continue Reading
The amygdala plays a key role in anxiety. Information from the environment reaches the amygdaloid basolateral nucleus and after its processing is relayed to the amygdaloid central nucleus where a… Continue Reading
RationaleSeveral studies have suggested the inhibitory control of adenosine (A)2A receptor stimulation in cocaine-induced behavioral actions.ObjectivesA combination of systemic or local drug… Continue Reading
Recent evidence has shown in membrane preparations that the binding of one ligand to its receptor is able to modify the binding parameters of a second receptor (receptor-receptor interactions),… Continue Reading
RationaleAccumulating evidence for the presence of GABAA ρ receptors within the amygdala which differ from other members of the GABAA receptor family in both subunit composition and functional… Continue Reading
RationaleThe amygdala plays a paramount role in the modulation of anxiety and numerous studies have shown that arginine vasopressin (AVP) elicits anxiogenic effects following either its systemic or… Continue Reading
Financiado por proyectos de MINECO: SAF2016-79008-P; PSI2017-82604-R y BES-2014-068426 Universidad de Malaga. Campus de Excelencia Internacional Andalucia Tech.