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  • Noriko Nakanishi, Yoshimi Nakagawa, +11 authors Hitoshi Shimano
  • Biology, Medicine
  • Biochemical and biophysical research…
  • 2009 (First Publication: 1 August 2009)
  • MicroRNAs (miRNAs) are short non-coding RNA that post-transcriptionally regulates gene expression. Some miRNAs have been proposed to be associated with obesity. However, miRNAs, which are related toContinue Reading
    We previously showed that CGP 42112 (an angiotensin type 2 [AT(2)] agonist) markedly reduces catecholamine biosynthesis by decreasing cGMP production mediated by AT(2), a subtype of Ang II receptorContinue Reading
  • Kazuhiro Takekoshi, Kiyoaki Ishii, Shunsuke Shibuya, Yasushi Kawakami, Kazumasa Isobe, Toshiaki Nakai
  • Chemistry, Medicine
  • Biochemical pharmacology
  • 2002 (First Publication: 1 March 2002)
  • It has been reported that endothelins (ETs) stimulate catecholamine release from chromaffin cells. However, it is not known whether ETs also affect catecholamine biosynthesis. Thus, using a ratContinue Reading
  • Toshiyuki Fukuda, Kazuhiro Takekoshi, Toru Nanmoku, Kiyoaki Ishii, Kazumasa Isobe, Yasushi Kawakami
  • Biology, Medicine
  • Biochimica et biophysica acta
  • 2005 (First Publication: 1 October 2005)
  • The small GTPase, RhoA, and its downstream effecter Rho-kinase (ROK) are reported to be involved in various cellular functions, such as myosin light chain phosphorylation during smooth muscleContinue Reading
  • Tadayoshi Karasawa, Akimitsu Takahashi, +16 authors Hitoshi Shimano
  • Biology, Medicine
  • Arteriosclerosis, thrombosis, and vascular…
  • 2011 (First Publication: 1 August 2011)
  • OBJECTIVE Sterol regulatory element-binding protein-1 (SREBP-1) is nutritionally regulated and is known to be a key transcription factor regulating lipogenic enzymes. The goal of this study was toContinue Reading