Kiwako Yamamoto-Hanada

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BACKGROUND Evidence is accumulating that early consumption is more beneficial than is delayed introduction as a strategy for primary prevention of food allergy. However, allergic reactions caused by early introduction of such solid foods have been a problematic issue. We investigated whether or not early stepwise introduction of eggs to infants with eczema(More)
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive multifactorial disease with limited treatment options. Aim: To evaluate the efficacy of glycosides based standardized fenugreek seed extract (SFSE-G) on behavioral, biochemical, molecular and ultrastructural changes in bleomycin (BLM) induced pulmonary fibrosis in the laboratory rats.(More)
Wolfram syndrome is a rare genetic disorder accompanying diabetes insipidus, sensorineural hearing loss, neurological complications, and psychiatric illness. This syndrome has been attributed to mutations in the WFS1 gene. In this study, we made a detailed histochemical analysis of the distribution of Wfs1 mRNA in the brain of developing mice. There were(More)
BACKGROUND Food allergy (FA) is one of the most important health issues in schoolchildren. Although one of the most common places where pediatric anaphylaxis occurs is the home of a peer, the perception and experiences of caregivers who do not have a child with FA are unclear. METHODS An anonymous paper-based questionnaire was distributed to caregivers of(More)
BACKGROUND In the past few decades, the prevalence of allergic diseases has increased rapidly worldwide. At the same time, the overuse of antibiotics has been observed, especially in Japan. OBJECTIVE To elucidate the association of early childhood antibiotic use with allergic diseases in later childhood at 5 years of age. METHODS Relevant data were(More)
Pain management for needle-related procedures is poor in Japan. In many countries the use of lidocaine/prilocaine cream for the relief of pain associated with venipuncture has been approved. In children, a psychological approach has also been shown to be effective in reducing pain with venipuncture. We developed a multidisciplinary procedure that combines a(More)
BACKGROUND Although recent studies suggest that eczema in early childhood is important in the development of food allergy, the importance of the timing of eczema onset has not been fully clarified. OBJECTIVE This study aim to identify an association between the timing of eczema onset and development of food allergy in a prospective birth cohort study. (More)
BACKGROUND The TOPICOP scale was developed previously for atopic dermatitis patients. It comprises 12 questions to assess patients' worries and beliefs about topical corticosteroids. The aim of this study was to translate TOPICOP into Japanese and evaluate its feasibility. METHODS We developed a Japanese version of TOPICOP from the original English(More)
BACKGROUND In recent years, a resurgence in the number of infants with vitamin D deficiency has been noted. In addition to seasonal differences in exposure to ultraviolet (UV) rays, regional differences in dietary habits and lifestyles may affect susceptibility to vitamin D deficiency. However, no studies have been conducted on infants in multiple regions(More)
BACKGROUND Although the beta-2 receptor agonist (B2RA) is occasionally prescribed in the prenatal period for women with preterm labor, few studies have referred to the long-term effects of intrauterine exposure to B2RA on fetus. We examined the association between intrauterine exposure to B2RA and asthma in the offspring. METHODS We obtained data from a(More)