Learn More
BACKGROUND Previous pathological and clinical studies demonstrated an intimal defect in patients with acute aortic intramural hematoma (IMH). The purpose of this study was to investigate the prevalence and clinical outcome of intimal defect detected by multidetector computed tomography (MDCT) in patients with IMH. METHODS AND RESULTS We retrospectively(More)
BACKGROUND  Limited data are available for sex-based differences in Japanese patients with acute myocardial infarction (AMI) undergoing primary percutaneous coronary intervention (PCI). METHODS AND RESULTS  The study patients comprised 1,197 women and 3,182 men who underwent primary PCI for AMI in 2005-2007. Compared with the men, the women were(More)
OBJECTIVE The management of asymptomatic severe and very severe aortic stenosis (AS) remains unestablished. This study aimed to investigate the clinical outcomes of severe versus very severe AS patients. DESIGN A single centre, retrospective cohort study. PATIENTS AND METHODS The study retrospectively reviewed 108 conservatively treated patients with(More)
We present Si nanotubes prepared by reductive decomposition of a silicon precursor in an alumina template and etching. These nanotubes show impressive results, which shows very high reversible charge capacity of 3247 mA h/g with Coulombic efficiency of 89%, and also demonstrate superior capacity retention even at 5C rate (=15 A/g). Furthermore, the capacity(More)
BACKGROUND Melanoma antigen genes (MAGE) and GAGE genes are encoded by genes that are silent in virtually all normal adult tissues but are expressed in tumors from various tissues. These gene products are targets for specific immunotherapy as they are presented by HLA I molecules and recognized by autologous cytotoxic T-lymphocytes. However, the(More)
OBJECTIVES Surgical papillary muscle (PM) imbrication has been reported to be effective to relieve leaflet tethering in patients with functional mitral regurgitation (FMR). However, the mechanism that contributes to improvement of FMR by shortening the interpapillary muscle distance (IPMD) has not been well investigated. The purpose of the present study was(More)
The pharmaceutical industry has great interest in organic molecular nanosized crystals because their enhanced solubility and dissolution rate can potentially enhance drug bioavailability. In this work, patterned engineered surfaces were used to crystallize glycine with a lateral dimension below 200 nm in a confined volume while controlling supersaturation.(More)
AIMS To prospectively evaluate the relationship between left atrial volume (LAV) and the risk of clinical events in patients with hypertrophic cardiomyopathy (HCM). METHODS We enrolled a total of 141 HCM patients with sinus rhythm and normal pump function, and 102 patients (73 men; mean age, 61±13 years) who met inclusion criteria were followed for(More)
OBJECTIVE Many patients with aortic stenosis (AS) have coexisting aortic regurgitation (AR). However, few data exist regarding its clinical significance and prognostic value. The aim of this study was to examine the effect of concomitant significant AR on clinical outcomes in patients with non-surgically treated severe AS. DESIGN A single centre,(More)
A 33-year-old woman with Wernicke's encephalopathy (WE) due to poor oral intake after allogeneic stem cell transplantation for acute myeloid leukemia showed a sequential development of bilateral gaze-evoked nystagmus (GEN), rightward gaze palsy, and upbeat nystagmus. Initial MRIs obtained when she had GEN only showed a lesion involving the medullary(More)