Kishore Sridharan

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BACKGROUND In patients with acute hypercapnic respiratory failure (AHRF) during exacerbations of COPD, mortality can be high despite noninvasive ventilation (NIV). For some, AHRF is terminal and NIV is inappropriate. However there is no definitive method of identifying patients who are unlikely to survive. The aim of this study was to identify factors(More)
Anorexia causing weight loss at high altitude (HA) is a major problem. Neuropeptide Y (NPY) and galanin are considered to have appetite regulatory function. The present study was therefore undertaken to investigate the changes in these two peptides at simulated HA and its possible role in anorexia. Male Sprague-Dawley rats (n = 8 in each group) were exposed(More)
UNLABELLED Low-dose CT screening for lung cancer is effective but expensive. Therefore, cheaper or more focused screening strategies may be required. LungSEARCH is a randomised prospective trial of 1568 high-risk individuals (ie, current or former moderate to heavy smokers with mild/moderate COPD) who undergo either annual sputum cytology/cytometry testing(More)
(1) Bornes sur le risque sous condition de marge, Massart & Nédélec [MN06] [Sujet libre] (2) Vitesses rapides en classication via du plug-in, Audibert & Tsybakov [AT07] [Élodie Vernet] (4) Sous-optimalité de la minimisation du risque empirique pénalisé en classication, Lecué [Lec07] [Stéphane Ivano] (5) Régularisation pour les méthodes à noyaux, Mendelson &(More)
DISCLAIMER This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government, nor any agency thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information,(More)
Oxidative stress due to excessive production of free radicals in living organisms during exposure to hypobaric hypoxia is well documented. In search of a suitable antioxidant from natural sources, in the present study effect of pomegranate (Punica granatum, family Punicaceae) juice (PG) was evaluated on glutathione levels and related enzymes in tissues of(More)
Fifty-two Indian military parachutist trainees were studied throughout the training period to investigate effects of stress in parachutist training on performance efficiency. Stress attributable to fear, anxiety, and apprehension about the inherent risk of paratrooping was studied along with physiological and biochemical changes. An attempt is made to(More)
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