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  • Robert E Wolfe, Guoqing Lin, James C Tilton, Alice R Isaacman, R E Wolfe, G Lin +3 others
  • 2014
[1] The Visible Infrared Imaging Radiometer Suite (VIIRS) sensor was launched 28 October 2011 on the Suomi National Polar-orbiting Partnership (SNPP) satellite. VIIRS has 22 spectral bands covering the spectrum between 0.412 μm and 12.01 μm, including 16 moderate resolution bands (M-bands) with a nominal spatial resolution of 750 m at nadir, five imaging(More)
Injury of isolated squid giant axons in sea water by cutting or stretching initiates the following unreported processes: (i) vesiculation in the subaxolemmal region extending along the axon several mm from the site of injury, followed by (ii) vesicular fusions that result in the formation of large vesicles (20-50 micron diameter), 'axosomes', and finally(More)
Human ClC-2 Cl(-) (hClC-2) channels are activated by protein kinase A (PKA) and low extracellular pH(o). Both of these effects are prevented by the PKA inhibitor, myristoylated PKI. The aims of the present study were to identify the PKA phosphorylation site(s) important for PKA activation of hClC-2 at neutral and low pH(o) and to examine the relationship(More)
The purpose of this study was to determine the mechanism of action of SPI-0211 (Lubiprostone), a novel bicyclic fatty acid, under development for the treatment of bowel dysfunction. Adult rabbit intestine was shown to contain mRNA for ClC-2 by RT-PCR, Northern analysis, and in situ hybridization. T84 cells grown to confluence on permeable supports were(More)
Our objective was to identify and localize a K+ channel involved in gastric HCl secretion at the parietal cell secretory membrane and to characterize and compare the functional properties of native and recombinant gastric K+ channels. RT-PCR showed that mRNA for Kir2.1 was abundant in rabbit gastric mucosa with lesser amounts of Kir4.1 and Kir7.1, relative(More)
It has been difficult to separate/identify the roles of ClC-2 and CFTR in Cl(-) transport studies. Using pharmacological agents, we aimed to differentiate functionally between ClC-2 and CFTR Cl(-) channel currents. Effects of CFTR inhibitor 172 (CFTRinh172), N-(4-methylphenylsulfonyl)-N'-(4-trifluoromethylphenyl)urea (DASU-02), and methadone were examined(More)
PURPOSE Effects of cis-unoprostone isopropyl, its primary metabolite M1, trans-unoprostone isopropyl, latanoprost free acid, and fluprostenol were studied on Ca(2+)-activated K(+) (BK) channels, plasma membrane potential, [cAMP](i), [cGMP](i), and steady state [Ca(2+)](i), and protection against endothelin-1 (ET-1)-induced steady state [Ca(2+)](i) increases(More)
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