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Viperin is an interferon-induced protein with a broad antiviral activity. This evolutionary conserved protein contains a radical S-adenosyl-l-methionine (SAM) domain which has been shown in vitro to… (More)
Flaviviruses are arthropod-borne viruses that constitute a major global health problem, with millions of human infections annually. Their pathogenesis ranges from mild illness to severe… (More)
Efficient antiviral immunity requires interference with virus replication at multiple layers targeting diverse steps in the viral life cycle. We describe here a novel flavivirus inhibition mechanism… (More)
Tick-borne encephalitis virus (TBEV) is a very important virus medically, causing mild or severe encephalitis often with long-lasting sequelae. Treatment of tick-borne encephalitis is limited to su… (More)
Viperin induces secretion of tick-borne encephalitis virus capsid particles by interacting with GBF1
Aims: Blood flow through human blood vessels is numerically analyzed. We investigated flow conditions in the aorta and in coronary arteries. Both steady and pulsatile blood flow is analyzed.… (More)