Kirstin Knox

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Several recent reports have documented the neuroinvasiveness of human herpesvirus-6 (HHV-6) in infants with primary HHV-6 infections, in children and adults with AIDS, in recipients of bone marrow transplants, and in immunologically intact adults and children. CNS infections with HHV-6 can be subacute and are frequently associated with diffuse or multifocal(More)
Severe interstitial pneumonitis in 2 marrow-transplant recipients was associated with human herpesvirus-6 (HHV-6) infection. The virus was repeatedly detected in respiratory specimens from 1 patient, and HHV-6-infected cells were shown in lung tissue from both patients by immunohistochemical staining. The infected cells were primarily intra-alveolar(More)
ii I certify that I have read this dissertation and that, in my opinion, it is fully adequate in scope and quality as a dissertation for the degree of Doctor of Philosophy. I certify that I have read this dissertation and that, in my opinion, it is fully adequate in scope and quality as a dissertation for the degree of Doctor of Philosophy. I certify that I(More)
Many methods of clustering proteins within large protein families either build up from pairwise sequence alignments or rely solely on hierarchical clustering methods. While these methods can be incredible useful, they may not efficiently discover small regions of similarity in large multidomain proteins, and they may miss functional similarities that arose(More)
T2-weighted gradient recalled (T2*) sequences are often used in place of T2 sequences when imaging the shoulder. The main advantages of these sequences are the decreased imaging time, the better demonstration of cartilage disorders, and the added tissue information that can be garnered due to the increased sensitivity to magnetic susceptibility with T2*(More)
The development of home orientation was evaluated in 2-14-day-old kittens nursing from mothers fed a protein-restricted or control diet during late gestation and lactation. Although restricted kittens remained in the home when placed in it, their ability to return to the home was delayed when they were removed from it. Restricted kittens also exhibited(More)