Kirsten van de Groep

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Respiratory infections are among the most important causes of morbidity and mortality from infectious diseases worldwide. The most common causative bacterium, Streptococcus pneumoniae, frequently colonises the upper respiratory tract, where it resides mostly asymptomatically. Occasionally, however, S pneumoniae can cause severe disease such as pneumonia.(More)
Methods Data were derived from a prospective cohort study in two tertiary ICUs in the Netherlands in 2011 and 2012. Patients were included if they had survived one year following a sepsis episode in the ICU. Health care consumption and reimbursed costs were derived from a database of a Dutch health insurance company. The medical ethics committee of the UMC(More)
The earliest studies in the late 19th century on Streptococcus pneumoniae (S. pneumoniae) carriage used saliva as the primary specimen. However, interest in saliva declined after the sensitive mouse inoculation method was replaced by conventional culture, which made isolation of pneumococci from the highly polymicrobial oral cavity virtually impossible.(More)
A1 Identification of distinct endophenotypes in patients with acute respiratory distress syndrome by unbiased cluster analysis, and their association with mortality L. Bos, L. Schouten, L. van Vught, M. Wiewel, D. Ong, O. Cremer, A. Artigas, I. Martin-Loeches, A. Hoogendijk, T. van der Poll, J. Horn, N. Juffermans, M. Schultz Academic Medical Center,(More)
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