Kirsten Szdzuy

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The production of heat (or thermogenesis) and its response to cold improve very quickly around birth in both mammals and birds. The mechanisms for such rapid perinatal development are not fully understood. Previous experiments with hyperoxia suggested that, during the last phases of incubation, eggshell and membranes might pose a limit to oxygen(More)
Marsupials represent only 6% of all living mammals. Marsupialia and Placentalia are distinguished mainly by their modes of reproduction. In particular, the differences in the stage of development of the neonates may be one explanation for the divergent evolutionary success. In this respect one important question is whether the survivability of the neonate(More)
We asked to what extent sustained hypoxia during embryonic growth might interfere with the normal development of thermogenesis. White Leghorn chicken eggs were incubated at 38 degrees C either in normoxia (Nx, 21% O2) or in hypoxia [Hx, 15% O2, from embryonic day 5 (E5) until hatching]. The Hx embryos had lower body weight (W) throughout incubation, and(More)
Two marsupial species (Monodelphis domestica, Macropus eugenii) and four eutherian species (Mesocricetus auratus, Suncus murinus, Tupaia belangeri and Cavia aperea) were examined to compare and contrast the timing of lung and metabolic development during the postnatal maturation of the mammalian respiratory apparatus. Using light, scanning and transmission(More)
We investigated the effects of sustained embryonic hypoxia on the neonatal ventilatory chemosensitivity. White Leghorn chicken eggs were incubated at 38 degrees C either in 21% O(2) throughout incubation (normoxia, Nx) or in 15% O(2) from embryonic day 5 (hypoxia, Hx), hatching time included. Hx embryos hatched approximately 11 h later than Nx, with similar(More)
Hypoxia during incubation results in hatchlings with a reduced thermogenic capacity and a blunted ventilatory (V (E)) chemosensitivity (Szdzuy, K., Mortola, J.P., 2007b. Ventilatory chemosensitivity of the 1-day-old chicken hatchling after embryonic hypoxia. Am. J. Physiol. (Regul. Integr. Comp. Physiol.) 293, R1640-R1649). We asked if similar effects(More)
This communication describes the application of the barometric technique to the measurements of the breathing pattern (tidal volume and breathing rate) and pulmonary ventilation (VE) in chicken embryos and hatchlings. The chamber-plethysmograph was separated into two sections, an animal compartment, maintained at incubation temperature, and a recording(More)
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