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Trends in pediatric urolithiasis: patient characteristics, associated diagnoses, and financial burden
BackgroundThe goal of this study was to examine national trends in hospitalization, emergency department (ED) utilization, secondary diagnoses, and charges associated with pediatric… Expand
Beneficial effects of intravenous pamidronate treatment in children with osteogenesis imperfecta under 24 months of age
- Kirsten Kusumi, Rose M Ayoob, S. Bowden, Susan E. Ingraham, J. Mahan
- Journal of Bone and Mineral Metabolism
- 1 September 2015
Osteogenesis imperfecta (OI) is an inherited disorder characterized by bone fragility and low bone mass. Low bone density and fracture is a cause of morbidity. Limited data exists on bisphosphonate… Expand
Pediatric Origins of Nephrolithiasis-Associated Atherosclerosis.
OBJECTIVES To determine if nephrolithiasis-associated atherosclerosis has pediatric origins and to consider possible association between kidney stones and atherosclerosis-related proteins. STUDY… Expand
Comparison of Risk Factors for Pediatric Kidney Stone Formation: The Effects of Sex
- A. Schwaderer, R. Raina, A. Khare, F. Safadi, S. Moe, Kirsten Kusumi
- Front. Pediatr.
- 12 February 2019
Background: Urinary stones are affecting more children, and pediatric stone formers have unique pathophysiology compared to adults. While adult stone formers are most frequently male, children have… Expand
Urinary stone disease in pediatric and adult metabolic bone clinic patients
Kidney stones are increasing in the pediatric and adult populations; similarly osteoporosis is increasingly recognized in children. While kidney stone formers are known to suffer from low bone… Expand
Overview of Monogenic or Mendelian Forms of Hypertension
Monogenic or Mendelian forms of hypertension are described as a group of conditions characterized by insults to the normal regulation of blood pressure by the kidney and adrenal gland. These… Expand
Pediatric nephrolithiasis and the link to bone metabolism
Purpose of review To review the recent publications describing the link between pediatric nephrolithiasis and bone metabolism. Recent findings Nephrolithiasis incidence is increasing in children and… Expand
Adolescents with urinary stones have elevated urine levels of inflammatory mediators
- Kirsten Kusumi, J. Ketz, V. Saxena, John D Spencer, F. Safadi, Andrew L Schwaderer
- 16 April 2019
Urinary stones are increasing in children, primarily during adolescence. Although urinary stones are often viewed in the context of intermittent stone events, increasing evidence indicates that… Expand
The Role of Endothelin and Endothelin Antagonists in Chronic Kidney Disease
Background: Endothelins (ET) are a family of peptides that act as potent vasoconstrictors and pro-fibrotic growth factors. ET-1 is integral to renal and cardiovascular pathophysiology and exerts… Expand
Bone mineral density in adolescent urinary stone formers: is sex important?
Urinary stone disease (USD) is affecting a greater number of children and low bone mineral density (BMD) and increased skeletal fractures have been demonstrated in stone patients; however, the… Expand