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Natural selection shaped regional mtDNA variation in humans
- D. Mishmar, E. Ruiz-Pesini, +10 authors D. Wallace
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 30 December 2002
It is concluded that selection may have played a role in shaping human regional mtDNA variation and that one of the selective influences was climate. Expand
Vertebral osteomyelitis: long-term outcome for 253 patients from 7 Cleveland-area hospitals.
A retrospective study of 253 patients with vertebral osteomyelitis who had long-term follow-up, finding that an optimal outcome of VO requires heightened awareness, early diagnosis, prompt identification of pathogens, reversal of complications, and prolonged antimicrobial therapy. Expand
Exogenous testosterone or testosterone with finasteride increases bone mineral density in older men with low serum testosterone.
- J. Amory, N. Watts, +5 authors J. Tenover
- The Journal of clinical endocrinology and…
- 1 February 2004
T therapy in older men with low serum testosterone levels increases vertebral and hip BMD over 36 months, both when administered alone and when combined with F, and suggests that dihydrotestosterone is not essential for the beneficial effects of T on BMD in men. Expand
Reduction in Fear of Falling Through Intense Tai Chi Exercise Training in Older, Transitionally Frail Adults
- R. Sattin, Kirk A Easley, S. Wolf, Ying Chen, M. Kutner
- Journal of the American Geriatrics Society
- 1 July 2005
Objectives: To determine whether an intense tai chi exercise program could reduce fear of falling better than a wellness education (WE) program in older adults who had fallen previously and meet… Expand
Inflammation and intestinal metaplasia of the gastric cardia: the role of gastroesophageal reflux and H. pylori infection.
The prevalence of cardia inflammation is similar in patients with and without GERD and is associated with H. pylori infection (P < 0.001) and intestinal metaplasia elsewhere in the stomach, indicating that it is distinct from Barrett's esophagus. Expand
Age‐ and gender‐related changes in the cellularity of human bone marrow and the prevalence of osteoblastic progenitors
- G. Muschler, H. Nitto, C. Boehm, Kirk A Easley
- Biology, Medicine
- Journal of orthopaedic research : official…
- 1 January 2001
Test of the hypothesis that human aging is associated with a significant change in the number or prevalence of osteoblastic progenitors in the bone marrow revealed a significant age‐related decline in theNumber of nucleated cells harvested per aspirate for both men and women. Expand
Aspiration to Obtain Osteoblast Progenitor Cells from Human Bone Marrow: The Influence of Aspiration Volume*
- G. Muschler, C. Boehm, Kirk A Easley
- The Journal of bone and joint surgery. American…
- 1 November 1997
The data confirm that humans differ significantly from one another with respect to the cellularity of bone marrow and the prevalence of osteoblast progenitor cells and recommend that, when bone marrow is obtained with aspiration for use as a bone graft, the volume of aspiration from any one site should not be greater than two milliliters. Expand
Fluid overload before continuous hemofiltration and survival in critically ill children: A retrospective analysis*
Survival in critically ill children receiving CVVH in this large series was higher than in previous reports, andCVVH survival may be associated with less percent fluid overload in patients with ≥3-organ MODS. Expand
Correlation between ammonia levels and the severity of hepatic encephalopathy.
Ammonia levels correlate with the severity of hepatic encephalopathy, and venous sampling is adequate for ammonia measurement, and there appears to be no additional advantage of measuring the partial pressure of ammonia compared with total ammonia levels. Expand
Clinical patterns, natural history, and progression of ulcerative colitis
Both the final disease destination and the initial diagnosis impacted cumulative colectomy-ileostomy rates and factors associated with extension were toxic colitis, extent of disease at diagnosis, and joint symptoms. Expand