Kiran Parkhe

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Circulating filarial antigen (CFA) isolated from the plasma of microfilaraemic patients was fractionated on an Ultrogel ACA 34 column. The second protein peak (CFA2) showing filarial antigen was further fractionated by DEAE-cellulose column chromatography into two fractions (CFA2 DE1 and DE2). CFA2 DE1 fraction, showing antigenic activity, was further(More)
A form of unexplained arthritis, not attributable to known causes, seen in children (0-14 yrs) in this endemic zone of Bancroftian filariasis was investigated for its association with filariasis. Nineteen cases of undiagnosed arthritis were screened for filarial IgG antibodies to Wuchereria by Stick Enzyme Linked Immunosorbent Assay (ELISA). All had large(More)
Sodium dodecyl sulphate-polyacrylamide gel electrophoresis of circulating filarial antigen fraction-2 isolated from plasma of microfilaraemic patients withWuchereria bancrofti infection has shown 21 bands with molecular weights ranging from 12 to 120 kDa. The gel (12 cm) was sliced at an interval of one cm and the eluates of all the gel slicesviz., CFA2-1(More)
The Wb E34 monoclonal antibody raised against Wuchereria bancrofti microfilarial excretory secretory (mf ES) antigen was reported to be useful in detecting the filarial antigen in W. bancrofti and Brugia malayi infected sera. Further studies in this laboratory showed that this monoclonal antibody reacts with a stage-specific antigen of W. bancrofti filarial(More)
Let M1 and M2 be two n-dimensional smooth manifolds with boundary. Suppose we glue M1 and M2 along some boundary components (which are, therefore, diffeomorphic). Call the result N. If we have a group G acting continuously on M1, and also acting continuously on M2, such that the actions are compatible on glued boundary components, then we get a continuous(More)
Detection of filarial antigen in different groups of sera was carried out by sandwich as well as inhibition enzyme-linked immunosorbent assays using antibody-coated sticks. Both systems were found to be equally sensitive in detecting antigen in 90% of microfilariae carriers. Incorporation of avidin-biotin in the sandwich assay system increased the(More)
Let M be a connected 1-manifold, and let G be a finitely-generated nilpotent group of homeomorphisms of M . Our main result is that one can find a collection {Ii, j , Mi, j } of open disjoint intervals with dense union in M , such that the intervals are permuted by the action of G, and the restriction of the action to any Ii, j is trivial, while the(More)
We show that if f : S1 × S1 → S1 × S1 is C2, with f(x, t) = (ft(x), t), and the rotation number of ft is equal to t for all t ∈ S1, then f is topologically conjugate to the linear Dehn twist of the torus ( 1 1 0 1 ) . We prove a differentiability result where the assumption that the rotation number of ft is t is weakened to say that the rotation number is(More)
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