Kira L Epstein

Learn More
The objective of this study was to determine the characteristics based on ultrasonographic examination of the stomach, duodenum, jejunum, cecum, and peritoneal fluid in normal adult ponies. Abdominal ultrasonographic examination was performed in nine unsedated standing ponies. The duodenum was examined at three sites and the jejunum in 12 regions. Wall(More)
BACKGROUND Critically ill horses are susceptible to thrombotic disease, which might be related to increased platelet reactivity and activation. OBJECTIVES To compare the effect of oral clopidogrel and aspirin (ASA) on equine platelet function. ANIMALS Six healthy adult horses. METHODS Horses received clopidogrel (2 mg/kg p.o. q24h) or ASA (5 mg/kg(More)
In many cases of equine infectious disease, long-term administration of antimicrobial drugs is required. Oral agents are preferred because of the relative ease of administration compared with other routes. Enrofloxacin has been shown to be effective against a variety of equine pathogens, but oral administration of this drug has proved difficult in horses.(More)
OBJECTIVE To determine whether topical application of 1% diclofenac sodium cream would decrease inflammation at sites of IV regional limb perfusion (IVRLP) in healthy horses. ANIMALS 6 healthy adult horses (12 forelimbs). PROCEDURES Bilateral IVRLP with 2.5 g of amikacin sulfate was performed twice in each horse, with 24 hours between each session.(More)
OBJECTIVE To review the hemostasis literature relevant to development of coagulopathy in the critically ill equine patient. DATA SOURCE Original scientific and review articles. HUMAN DATA SYNTHESIS Inflammation plays a critical role in the activation and amplification of clot formation, as well as the impairment of physiologic anticoagulant mechanisms,(More)
OBJECTIVE To determine (1) if clinically useful concentrations of amikacin sulfate can be obtained in synovial fluid during regional limb perfusion (RLP) performed above the carpus in standing sedated horses and (2) to determine the efficacy of 3 tourniquet types (narrow rubber [NR], wide rubber [WR], pneumatic [PN]). ANIMALS Horses (n=9). METHODS(More)
The objective was to characterize ultrasonographic changes in bowel wall thickness, contractility, degree of distension, luminal contents, and peritoneal fluid associated with exploratory celiotomy in normal ponies. Gastrointestinal ultrasonographic examination was performed in 14 ponies on days 1, 3, 5, and 7 after an exploratory celiotomy. Wall thickness,(More)
OBJECTIVES To compare in vitro physical and mechanical characteristics of 1-layer and 2-layer end-to-end jejunoileostomy. STUDY DESIGN In vitro experimental study. ANIMALS Adult horses (n = 6). METHODS Harvested equine jejunum and ileum was used to create 1- and 2-layer end-to-end jejunoileostomy specimens. Construction time, bursting pressure, and(More)
OBJECTIVES To (1) compare postoperative complications and survival in horses after small intestinal resection and anastomosis using 2 anastomosis techniques (single layer Lembert; double layer simple continuous oversewn with Cushing), and (2) to compare outcome by anastomosis type (jejunoileostomy; jejunojejunostomy). STUDY DESIGN Retrospective case(More)
REASONS FOR PERFORMING STUDY Accurate measurement of plasma fibrinogen concentrations is an important tool for assessment of horses with inflammatory diseases. OBJECTIVES To determine the precision and accuracy of a benchtop instrument using both fresh and frozen equine plasma by comparing the plasma fibrinogen concentration measured by a benchtop(More)