- Full text PDF available (3)
BACKGROUND Characterising intra and inter-subject variability of motor-evoked potential (MEP) measurements from transcranial magnetic stimulation (TMS) is key to its development as a diagnostic tool. METHODS We performed three experiments to elucidate MEP variability within subjects: (i) repeated measurements at different levels of stimulation and muscle… (More)
BACKGROUND The protozoan parasite Leishmania donovani (LD) reduces cellular cholesterol of the host possibly for its own benefit. Cholesterol is mostly present in the specialized compartment of the plasma membrane. The relation between mobility of membrane proteins and cholesterol depletion from membrane continues to be an important issue. The notion that… (More)
Xenograft trials allow tumor growth in human cell lines to be monitored over time in a mouse model. We consider the problem of inferring the effect of treatment combinations on tumor growth. A piecewise quadratic model with flexible phase change locations is proposed to model the effect of change in therapy over time. Each piece represents a growth phase,… (More)
The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This paper presents a method for semi-automatic analysis of morphometry in image cytometry studies. We examine morphological changes in neuroblastoma cells caused by a toxin. Nuclei are automatically recognized from images using a constrained seeded region growing algorithm. The shape of the nuclei is quantified by fitting ellipses to the identified… (More)