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To compare the management of postoperative pain using morphine administered by epidural catheter with intravenous patient-controlled analgesia (PCA), we prospectively studied 47 consecutive cases involving repair of the anterior cruciate ligament of the knee. Both the quality of analgesia and the incidence of side effects were documented. Compared with… (More)
The use of epidural morphine for postoperative analgesia outside of intensive care units remains controversial. In this report our anesthesiology-based acute pain service documents experience with 1,106 consecutive postoperative patients treated with epidural morphine on regular surgical wards. This experience involved 4,343 total patient days of care and… (More)
The International Cellular Therapy Coding and Labeling Advisory Group was established to address the growing need for standardization of terminology and labeling for cellular therapy products as a result of increasing international transfer of these products. This paper presents new standards for terminology and labeling. These standards have been developed… (More)
The management of postoperative pain with continuous epidural fentanyl infusion was compared with continuous intravenous fentanyl infusion. In a randomized, doubleblind protocol we prospectively studied 20 patients undergoing repair of the anterior cruciate ligament of the knee. The quality of analgesia and the incidence of side effects were documented.… (More)
The publication of new standards for terminology and labeling marks an important step in ensuring consistency and traceability of cellular therapies at the global level. However, it is only with the widespread implementation of the standard that the benefits can be truly realized. This paper provides guidance on the practical aspects of adopting these new… (More)
We report a case of successful resuscitation and clinical management in a 31-year-old man who allegedly ingested 20 g of cocaine hydrochloride. The physiologic and pharmacologic mechanisms of cocaine toxicity are reviewed. The use of labetalol in resolving the cardiovascular crisis is specifically detailed.
This report surveyed the pharmacologic knowledge of the physician housestaff and intensive care nurses regarding the analgesic and anxiolytic effects of narcotics, benzodiazepines and neuromuscular blockers. The results demonstrated a commonly held misconception that muscular paralysis is a calm and painless state. The authors instituted an educational… (More)
Let R be an integral domain and let f (X) be a nonzero polynomial in R[X]. The content of f is the ideal c(f) generated by the coefficients of f. The polynomial f (X) is called Gaussian if c(f g) = c(f)c(g) for all g(X) ∈ R[X]. It is well known that if c(f) is an invertible ideal, then f is Gaussian. In this note we prove the converse.
The classical ring of integer-valued polynomials Int(Z) consists of the poly-nomials in Q[X] that map Z into Z. We consider a generalization of integer-valued polynomials where elements of Q[X] act on sets such as rings of algebraic integers or the ring of n × n matrices with entries in Z. The collection of polynomials thus produced is a subring of Int(Z),… (More)