Kimberly J Durniak

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Structural studies of the T7 bacteriophage DNA-dependent RNA polymerase (T7 RNAP) have shown that the conformation of the amino-terminal domain changes substantially between the initiation and elongation phases of transcription, but how this transition is achieved remains unclear. We report crystal structures of T7 RNAP bound to promoter DNA containing(More)
Since its founding in 1780, the American Academy has served the nation as a champion of scholarship, civil dialogue, and useful knowledge. As one of the nation's oldest learned societies and independent policy research centers, the Academy convenes leaders from the academic, business, and government sectors to address critical challenges facing our global(More)
The Yale Graduate Student Research Symposium (GSRS) is an annual event organized solely by graduate students. The GSRS is an open forum for sharing and learning about the research being conducted by the next generation of scientists-today's graduate students. This year, on November 1, 2002, some 300 Yale researchers-from graduate students to distinguished(More)
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