Kimberly J Durniak

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Structural studies of the T7 bacteriophage DNA-dependent RNA polymerase (T7 RNAP) have shown that the conformation of the amino-terminal domain changes substantially between the initiation and elongation phases of transcription, but how this transition is achieved remains unclear. We report crystal structures of T7 RNAP bound to promoter DNA containing(More)
The Yale Graduate Student Research Symposium (GSRS) is an annual event organized solely by graduate students. The GSRS is an open forum for sharing and learning about the research being conducted by the next generation of scientists today's graduate students. This year, on November 1, 2002, some 300 Yale researchers from graduate students to distinguished(More)
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