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1. A randomly labelled 14C protein was synthesized in order to investigate the site and rate of digestion and absorption of dietary protein in the rat. 2. A liquid test meal consisting of protein and a non-absorbable marker, 51CrCl3, was administered to rats which were then sacrificed at intervals up to 4 hr after ingestion of the meal. Analysis of(More)
The effects of pancreatic duct ligation on the digestion and absorption of a randomly 14C-labeled protein meal has been investigated in the rat. Although there was a significant reduction in luminal digestion and absorption of the protein meal in the pancreatic duct-ligated animals compared with controls, 37% of administered protein was absorbed despite(More)
Serum galactosyltransferase activity was found to be elevated in patients with alcoholic and other liver disorders but remained at a normal level in patients with a variety of nonhepatic diseases. The properties of the galactosyltransferase in patients with liver disease were compared with those of the enzyme in the serum of normal subjects. The possible(More)
Pediatric HIV infection remains a global health crisis with a worldwide infection rate of 2.5 million (WHO, Geneva Switzerland, 2009). Children are much more susceptible to HIV-1 neurological impairments compared with adults, which is exacerbated by coinfections. A major obstacle in pediatric HIV research is sample access. The proposed studies take(More)
Pediatric human immunodeficiency virus (HIV-1) infection remains a global health crisis. Children are much more susceptible to HIV-1 neurological impairments than adults, which can be exacerbated by coinfections. Neurological characteristics of pediatric HIV-1 infection suggest dysfunction in the frontal cortex as well as the hippocampus; limited MRI data(More)
The digestion, absorption, and intestinal propulsion of a14C-labeled protein meal were examined in rats with a 70% proximal small bowel resection at one and at six weeks after surgery. In addition, rats were studied one week after 70% small bowel resection plus ileocecal valve bypass. Comparison with sham-operated controls showed no significant impairment(More)
Protein digestion and absorption was studied in rats with 6-week-old surgically constructed self-filling intestinal blind loops and steatorrhea, ie, blind-loop animals and controls were fed a 14 C-labeled protein meal containing a nonabsorbable marker, 51 CrCl 3 , and sacrificed 1 or 2 hr later. Intestinal contents were analyzed for 14 C, 51 Cr, protein,(More)
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