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  • Aleksandr Lazaryan, Rachid Baz, +16 authors Frederic J. Reu
  • Medicine
  • 2010 (First Publication: 19 November 2010)
  • Abstract 1967 Background: An initial report of MM011 described the MTD and promising activity in the first 62 patients (pts) (Baz R et al, Ann Oncol 2006). Here we report complete outcomes of theContinue Reading
  • Aleksandr Lazaryan, Mohamad A. Hussein, +16 authors Rachid Baz
  • Medicine
  • American journal of hematology
  • 2014 (First Publication: 1 April 2014)
  • A previous interim report of MM-011, the first study that combined lenalidomide with anthracycline-based chemotherapy followed by lenalidomide maintenance for relapsed and/or refractory multipleContinue Reading
  • Frederic J. Reu, Shahper Nazeer Khan, +16 authors Yogen Saunthararajah
  • Medicine
  • 2012 (First Publication: 16 November 2012)
  • Abstract 5031 Background: Myeloma inevitably becomes refractory to available agents primarily due to accumulation of genetic and epigenetic mutations in the aberrant clone. The s-phase dependent DNAContinue Reading
  • Frederic J. Reu, Dale R. Grabowski, +17 authors Mitchell R Smith
  • Medicine
  • 2015 (First Publication: 20 May 2015)
  • 8584 Background: Azacitidine (AZA) may overcome drug resistance of relapsed or refractory multiple myeloma (RRMM).Continuous administration should maximize epigenetic effects and safety. Methods:Continue Reading