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Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose.
The enhancing immune response and anti-inflammatory effects of Anemarrhena asphodeloides extract in RAW 264.7 cells.
Puerarin suppresses AGEs-induced inflammation in mouse mesangial cells: a possible pathway through the induction of heme oxygenase-1 expression.
Magnolol Suppresses Vascular Endothelial Growth Factor-Induced Angiogenesis by Inhibiting Ras-Dependent Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase/Akt Signaling Pathways
It is demonstrated that magnolol is an inhibitor of angiogenesis and suggested that this compound could be a potential candidate in the treatment ofAngiogenesis-related diseases.
Timosaponin AIII inhibits melanoma cell migration by suppressing COX‐2 and in vivo tumor metastasis
Results indicate that timosaponin AIII has the capacity to inhibit melanoma cell migration, an essential step in the process of metastasis, by inhibiting expression of COX‐2, NF‐κB, P GE2, and PGE2 receptors.
Dual Protective Effects of Flavonoids from Petasites japonicus against UVB-Induced Apoptosis Mediated via HSF-1 Activated Heat Shock Proteins and Nrf2-Activated Heme Oxygenase-1 Pathways.
The isolated compounds activated the Nrf2 and HSE pathways and could protect against UVB-induced apoptosis and could activate nuclear factor and heat-shock response transcription elements that resulted in the induction of heme oxygenase-1 and HSP70, respectively.
New coumarins isolated from the stem bark of Fraxinus rhynchophylla inhibit human neutrophil elastase and LPS-induced inflammation in RAW 264.7 cells
Coniferaldehyde inhibits LPS-induced apoptosis through the PKC α/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells.
Protective effects of Timosaponin AIII against UVB- radiation induced inflammation and DNA injury in human epidermal keratinocytes.
- Ki Mo Kim, A. Im, Se Kyu Park, Hyoung Seok Shin, S. Chae
- Biology, MedicineBiological and Pharmaceutical Bulletin
- 2 July 2019
Understanding into the molecular action of TA-III, a naturally occurring steroidal saponin separated from Anemarrhena asphodeloides, can useful for developing photoprotective agents is supported.
Phycocyanin Protects Against UVB-Induced Apoptosis Through the PKC α/βII-Nrf-2/HO-1 Dependent Pathway in Human Primary Skin Cells
Results demonstrate that Pc-induced expression of HO-1 is mediated by the PKC α/β II-Nrf-2/HO-1 pathway, and inhibits UVB-induced apoptotic cell death in primary skin cells.