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BACKGROUND/AIMS Oxidative stress results in protein oxidation and is implicated in carcinogenesis. Sulfiredoxin (Srx) is responsible for the enzymatic reversal of inactivated peroxiredoxin (Prx). Nuclear factor E2-related factor 2 (Nrf2) binds to antioxidant responsive elements and upregulates the expression of Srx and Prx during oxidative stress. We aimed(More)
Stem-cell-based regenerative medicine, especially in the last decade, has offered great opportunities for investigating fundamental biological processes and treating devastating diseases and injuries. In particular, human embryonic stem cells (hESCs) have two distinctive abilities: to self-renew for an unlimited number of generations and to differentiate(More)
CASE REPORT A 1-year-old girl presented with a 10-month history of progressive protuberance of the left frontal skull. Magnetic resonance imaging and computed tomography demonstrated a large osteolytic interosseous mass extending to the frontal sinus and temporal base without any intracranial invasion. A fronto-temporo-parietal craniectomy of the outer(More)
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